I’ve been on 5mg min and 1.25mg fin daily for a few months and I’m still waiting for a year to make a visual assessment, however my family’s genetics are quite aggressive so I’m thinking about the possibility of escalating to Dutasteride if needed later on.
However, if I need to escalate I’m thinking of trying 1 and then 2 weekly dutasteride doses in combination with daily fin and min, as intermediate escalations to evaluate the effectiveness of over 6-12 months respectively, thus not escalating beyond what is necessary. Then it would be daily 0.5mg Avodart + min as the ultimate final step if needed, without fin.
I’ve had no sides on min and fin which is a good sign, but still for both minimising unnecessary drug consumption plus economics, I’m thinking of these intermediate steps. Especially since dut has a long half life and works at equal levels to fin at 2 weekly doses, I’m thinking the constant DHT suppression of 1-2 weekly dut on top of fin would provide less of an up and down in DHT suppression, plus some more reduction from type I, without going straight to full nuclear 92-95% reduction from the beginning. From what I’ve seen type I is also more relevant than type II for the neurological side of things, but also there is allegedly uncertainty for dut crossing the blood brain barrier so unsure which side to be on regarding that. Nevertheless, I believe taking it slow and observing how I react over time would be wiser given the extreme half life and strength of the drug.
I’m aware of some doctors prescribing these intermediate dosages and people on here mentioning weekly dut, so I was wondering what your experiences have been, if you are currently or were in the past taking combination therapy of fin and dut together, or some similar regimen / strategy as discussed above.
TLDR: If you have or have taken 1-2x weekly dut, share your experiences
Trying 1-2x weekly dutasteride alongside your current routine might help balance efficacy and minimize unnecessary drug use. Dut is stronger than fin, targeting both type I and II DHT. Due to its long half-life, weekly dosing can still be effective. For shared experiences, check threads for similar regimens. The Beginner’s Guide might also have insights.