Hi everyone,
I’m looking for some “genetic detective” help. I’m currently cruising on 150-250mg Testosterone per week and I’ve been using 1mg - 1.25mg Finasteride daily as a preventative measure.
I’m considering adding a DHT-derivative (specifically Primobolan or potentially Masteron), but I’m terrified of hair loss. Since Finasteride doesn’t protect against DHT-derivatives, I pulled my raw DNA data from MyHeritage to see if I have the “protective” genes or the “hair reaper” genes.
I’ve identified a few markers, but I’d love a second opinion on my overall risk profile for Male Pattern Baldness (MPB) and how “safe” I am to run Primo.
My DNA Markers (RSIDs):
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rs615204 (Chr 1): TT
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rs61527094 (Chr 3): GG
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rs61528371 (Chr 3): AA
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rs61529892 (Chr 4): TT
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rs61524171 (Chr 6): CC
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rs61522264 (Chr 6): CC
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rs61527129 (Chr 8): CC
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rs61520309 (Chr 11): CC
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rs615290 (Chr 11): CC
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rs61528732 (Chr 11): CT
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rs61529638 (Chr 11): TT
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rs61521510 (Chr 17): GG
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rs61521756 (Chr 22): CC
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rs615213 (Chr X): AA
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rs61525850 (Chr X): CC
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rs73622812 (Chr 20): AA
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rs2180439 (Chr 20): CC
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rs1160312 (Chr 20): AG
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rs1041668 (Chr X): AA
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rs5919325 (Chr X): GG
Specific questions for the experts here:
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Overall MPB Risk: Based on my Chromosome 20 (rs1160312 AG / rs2180439 CC) and my X-chromosome (rs5919325 GG), how prone am I to natural MPB?
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Finasteride Necessity: Given my genetics, is the Finasteride actually doing heavy lifting on my current Test dose, or am I genetically “safe” anyway?
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The Primo Test: With my specific AR-gene (rs5919325 GG), can I likely get away with adding Primobolan without nuking my hairline?
I currently have a full head of hair and no noticeable recession, but I want to be smart before adding compounds that bypass the 5-alpha reductase enzyme.
Thanks in advance for the help!