Thats it guys no hope for me. I dont have a chance im 41/ south asian and iv left it too late. What advice can you give me ? I cant take oral fin/dut as i already have a bit of gyno
Even if it feels late, you still have options. Since you can’t take oral fin/dut due to gyno concerns, consider using topical fin or dut, as they tend to have fewer side effects. Topical min can also help to stimulate growth. Microneedling can be combined to improve results. Check out The Beginner’s Guide for more info on these treatments. Hair transplants are another option if combined with treatments to maintain results long-term.
Have you considered topical finasteride, it has minimal if not minimal less systemic impact than oral finasteride. From 0.005% to 0.1%, though 0.3% is on the upper end and may expose you to same amount of finasteride molecule despite topical application.
Below is how you can regrow your hair efficiently, unlikely minoxidil will do it for you:
PP405 or some other HFSC-targeting medicine is probably your only hope. Indirect DPC signalling is going to be a dead end for you. I have no damn idea also why in 2025, not a single drug that targets HFSCs had been developed, they are the missing link to treating baldness if not curing it far more efficiently. A drug that targets HFSCs in my belief will leave minoxidil in the dust as a regrowth agent. There exists ZERO medicines available that make use of such targets. I am afraid you are otherwise hopeless.Yeah 18 days had elapsed but I still see it worth answering. Hair loss is only partially reversible at those stages, is fully (if you respond well) reversible in earlier stages. Minoxidil does not work like a miracle, ignore the upvoted hyper-responders on r/tressless, and don’t get fooled on the hype that surrounds it. The reality is that many people maintain and see some regrowth (moderate) but not “dense” regrowth. For oral your chances (oral minoxidil) are higher but it comes with sides, I got sides on oral minoxidil, you may try though under a doctor’s prescription and get your BP tested to see it yourself, you are gonna be fine in all likelihood statistically speaking.
You then would need CB-03-01 and GT20029. But these medicines (or molecules as of yet) are not approved as medicines. Without finasteride/dutasteride the fight leads to a dead end, that is the truth. If you cannot use any 5ARI or anti-DHT medications then your only hope is again something that A)degrades the androgen receptors that androgens like DHT bind, something that B)occupies the space of receptors itself instead by binding them so DHT cannot bind to them and cause hair loss. Alternatively you may couple them in the future if they come up with a hair transplant (PP405+CB-03-01+GT20029), and you can get a significant amount of hair back. Or you could get on topical finasteride as I just mentioned
I ignored minoxidil because it won’t bring you the hair you had in childhood, this is the raw truth. Though you can get a partial reversal. 5% topical minoxidil with tretinoin or oral minoxidil. Topical works itself too for some but tretinoin turns you into a responder from non-responder. SULT1A1 is upregulated via tretinoin.
PS:This text is NOT a medical advice, always consult with a relevant healthcare professional before using any medications.