November 2024 – First Half
A study on γδT lymphocytes shows their potential in treating autoimmune conditions like alopecia areata (AA) by preventing lesion development and promoting hair regrowth. Combination therapies, such as platelet-rich plasma (PRP) and minoxidil, have demonstrated significant regrowth in severe AA cases, offering alternatives to corticosteroids. Mesenchymal stem cells from umbilical cord blood showed superior efficacy over minoxidil in treating androgenic alopecia in animal models. The impact of pH levels on hair health was examined, revealing that products with a pH between 5 and 7 are optimal for maintaining hair integrity. A systematic review of placental extracts suggested potential benefits for hair loss treatment, though evidence remains inconclusive. Emerging therapies include SAMiRNA technology targeting androgen receptors in androgenetic alopecia and light-based therapies like low-level laser therapy, showing promise as safe alternatives. The study of haircare practices linked chemical treatments and tight hairstyles to earlier onset of scarring alopecia. Fermented ginsenosides from kimchi bacteria demonstrated potential in promoting hair growth, surpassing finasteride in efficacy. Research on allergic contact dermatitis associated with men’s personal care products identified common allergens in hair loss treatments. A qualitative review of misinformation about alopecia highlighted the prevalence of myths and the importance of healthcare professionals in correcting misconceptions. A study on acute donor effluvium following FUE hair transplants found that extensive procedures increase the risk of hair loss in the donor area, suggesting a need for careful planning in surgeries.
The community discussed finasteride and minoxidil, both oral and topical, and affordable options via Amazon, sharing experiences with oral Propecia and minoxidil combinations, and topical treatments for enhanced results. Emphasis on DHT level measurement and dutasteride for finasteride non-responders, with genetic factors influencing treatment efficacy and unpredictable responses to medications. Scientific chatter includes creatine’s impact on DHT and the Bile Acid-Mediated DHT Dysregulation Hypothesis linking bile acids to hair loss. Clascoterone studies and microneedling as complementary treatments are explored, with debates on regimen effectiveness and treatment selection challenges, leading some to shave. Discussions on hair transplants and native versus transplanted hair reliability highlight early intervention and realistic expectations.