Best of Tressless Roundup

November 2025 – End of Month

Recent hair loss research, especially for androgenetic alopecia, reveals promising treatments. Apigenin promotes hair growth topically, while botulinum toxin enhances hair transplant outcomes. Targeting fibrosis could improve treatment efficacy. Plant-derived nanovesicles deliver finasteride effectively, and exosome-based therapies are being standardized for immune modulation and hair regeneration. Natural remedies like Croton tiglium Linn. and rosemary oil are explored for hair growth, with herbal hair oils and polyherbal hair dye creams as chemical alternatives. Estetrol may prevent hair loss in women, while zinc deficiency doesn’t significantly impact hair loss. A systematic review links androgenetic alopecia to anxiety, depression, and low self-esteem. Conjugated linoleic acid-based nanovesicles and platelet-rich plasma are explored for follicle rejuvenation. Novel biomarkers and drug targets like SOD1 and KL offer new treatment avenues.

The community discusses hair loss management, focusing on finasteride and minoxidil, with users tweaking finasteride dosages to mitigate side effects like anxiety and brain fog, and exploring topical alternatives to avoid chest soreness and gynecomastia. The oral versus topical applications debate persists, with some favoring sprays for safety. The efficacy of dermarollers and microneedling is under scrutiny, while concerns about side effects and interactions with Accutane prompt regimen adjustments. Experiences with hair transplants reveal psychological and financial burdens, leading some to consider stopping due to lack of progress. The quest for reliable oral minoxidil sources underscores authenticity and safety concerns, with advice to consult dermatologists. Emphasis on oral medications over topicals is evident, with progress journals showing mixed results; some report significant regrowth after switching to oral formulations, while others hit plateaus. The community explores diverse strategies, sharing insights to navigate hair loss management complexities.