October 2025 – First Half
Research in hair loss treatments highlights minoxidil as crucial for regrowth, with oral formulations enhancing density in non-scarring alopecia. Combining minoxidil and finasteride is more effective for male androgenetic alopecia, though finasteride and dutasteride may cause psychological side effects. Innovative delivery systems like stevioside-based and hyaluronic acid microneedles enhance minoxidil’s transdermal delivery. Microneedling with drugs and stem cells and exosome complexes show potential in androgenetic alopecia treatment. Platelet-rich plasma (PRP) benefits hair transplantation, with the single spin PRP method being cost-effective. Multimodal approaches combining PRP and mesotherapy are effective for chemically aggravated alopecia. Emerging treatments include RF-mesotherapy with bicalutamide and deep eutectic solvents for essential oil delivery. Chitosan with microneedling is under exploration. Telogen effluvium linked to metabolic stress from weight loss is temporary. A review of androgenetic alopecia emphasizes early intervention.
The community discusses finasteride and dutasteride challenges, particularly transitioning due to side effects like brain fog and libido issues, with some switching to dutasteride for potentially fewer side effects. Effectiveness scrutiny of finasteride leads users to consider alternatives like pyrilutamide and RU58841. Combining treatments such as finasteride with minoxidil and ketoconazole, and microdosing to reduce side effects, are hot topics. Concerns about oral minoxidil’s long-term safety and its shedding impact prompt users to seek management advice. Monitoring and tracking treatment progress, sharing journeys, and evaluating minoxidil side effects like pericardial effusion, with some considering stopping due to inconvenience, are key discussions. The psychological impact of hair loss, stress management, psychiatric support, and the role of diet in treatment side effects, especially with finasteride, are explored. The community seeks advice on early treatment and combining approaches for effective hair loss management.