Best of Tressless Roundup

August 2025 – End of Month

A systematic review of PRP therapy shows promise for androgenetic alopecia, though standardization is needed, while a prospective cohort study links elevated TNF-α levels to increased telogen effluvium risk post-PRP, suggesting patient-specific considerations. Exosomes from PRP enhance hair regeneration via the SIRT1/FoxO3a pathway, reducing oxidative stress. A comparative study finds oral minoxidil more effective than topical for male pattern hair loss, and a novel dietary supplement boosts androgenic alopecia treatments. A retrospective analysis supports a topical mix of tacrolimus, clobetasol, and minoxidil for primary cicatricial alopecias. Emerging therapies include microneedling with halometasone for alopecia areata and light-based therapies for various hair loss types. Natural remedies like rice water and CBD are under review for hair growth and texture. A systematic review links vitamin D and iron-rich foods to hair loss prevention, while alcohol and sugary drinks may worsen it. In adolescents, seborrheic alopecia is tied to hormones, stress, and lifestyle, with treatments including medication and lifestyle changes. A cross-sectional survey shows COVID-19 increases telogen effluvium, especially in women. Environmental factors, as a case report highlights, show shared combs can spread tinea capitis, emphasizing trichoscopy’s diagnostic importance.

The community discusses transitioning between finasteride and dutasteride, with reports of increased shedding and side effects prompting debates on sticking with current regimens or exploring RU58841 and Xyon. Concerns about oral versus topical treatments are prevalent, with some considering microneedling or hair transplants. The impact of alcohol and nicotine on hair health is under scrutiny, with some contemplating quitting to improve outcomes. Promising developments like PP405 for stimulating hair follicle stem cells and fucoidan for reversing hair loss and reducing inflammation in androgenetic alopecia are sparking interest. Users seek advice on managing side effects from dutasteride and minoxidil, with some considering exosome therapy as a next step, while the community shares experiences for effective hair loss management.