July 2025 – First Half
Camellia japonica seed extract and serotonin activate dermal papilla cells and stem cells for hair growth, while TGF-β1 and FGF-18 elucidate hair loss mechanisms, with Minoxidil’s efficacy noted. Bio-pulsed avian MSC-derived extracellular vesicles enhance regrowth and rejuvenation, and thrombin-preconditioned mesenchymal stem cell-derived exosomes aid wound healing, indirectly benefiting hair. Human amniotic stem cell exosomes show promise for androgenetic alopecia. Oral supplements, topical lotion, and mesotherapy reduce loss and increase density, while shampoo with VCO and Tectona grandis leaf extract boosts growth, with geographic influence noted. Hydrogel microneedles with bFGF and PVP-modified iridium nanoparticles improve the follicular microenvironment, surpassing minoxidil. Dutasteride microinfusion and microneedling are effective for male loss. CXCL12 in reversible fibroimmune remodeling suggests therapeutic targets. Platelet-rich plasma (PRP) enhances growth in androgenic alopecia, especially with minoxidil, and AI-based trichoscopy assesses effects. Saw palmetto, horsetail, pumpkin seed oil, and curcumin address female loss. TrichoConcept™ vehicle line is evaluated for personalized treatments, and Biosea® Revive Serum is confirmed safe and effective.
The community continues hair loss treatments, focusing on finasteride and minoxidil, with users navigating between oral and topical forms due to side effects or efficacy concerns. Some are switching from oral to DIY topical finasteride due to side effects, while others consider the reverse after limited success with topical applications. Concerns about side effects like increased body hair and erectile dysfunction lead to dosage adjustments and alternatives like dutasteride. Users are evaluating long-term effectiveness, with some questioning efficacy after extended use and considering options like microneedling or hair transplants. Research and experimentation with treatment combinations continue, with discussions on the combination of minoxidil and alfatradiol and the dilution of finasteride in topical solutions. The community also discusses the timing and application of treatments, such as wax and sunscreen application post-minoxidil use, and the benefits of adding topical minoxidil to an oral regimen, highlighting a commitment to finding effective solutions and sharing knowledge.